MASCARA
This is the makeup item you should be most vigilant about: As the brush is taken out, applied, and put back in the tube, it brings with it any bacteria that has collected along the way. Lingering bacteria can cause redness and itchiness, or even conjunctivitis and sties. Switch mascara every two to three months to be safe. It will also have a distinct gasoline-like smell once it's gone bad. If you develop any negative symptoms, immediately throw out any of your eye makeup that may have been contaminated. If your eyes are still irritated a day or two later, see your doctor.
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